neurology

Dr. M’s Women and Children First Podcast #76 – Ken Pelletier, MD, PhD – Choice and Love

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Kenneth R. Pelletier, MD, PhD is a Clinical Professor of Medicine, Department of Medicine; Department of Family and Community Medicine, and Department of Psychiatry at the University of California School of Medicine (UCSF) in San Francisco. He is Director of the Corporate Health Improvement Program (CHIP) which is a collaborative research program between CHIP and 15 of the Fortune 500 corporations including Ford, Oracle, Prudential, Apple, Dow, Lockheed Martin, Pepsico, IBM, American Airlines and NASA.

Dr. Pelletier served as Clinical Professor of Medicine at the University of Arizona School of Medicine and Stanford University School of Medicine. He was a Woodrow Wilson Fellow, studied at the CG Jung Institute in Zurich, Switzerland and has published over 300 professional journal articles in behavioral medicine, disease management, worksite interventions, alternative/integrative medicine, and epigenetics.

At the present time, Dr. Pelletier is a medical and business consultant to the US Department of Health and Human Services, the World Health Organization (WHO), the National Business Group on Health, the Federation of State Medical Boards, and major corporations including Cisco, IBM, American Airlines, Prudential, Dow, Disney, Ford, Mercer, Merck, Pepsico, Ford, Pfizer, Walgreens, NASA, Microsoft ENCARTA, Blue Cross/Blue Shield, United Healthcare, Health Net, the Pasteur Institute of Lille, the Alpha Group of Mexico, and the Singapore Ministry of Health.

Dr. Pelletier is the author of fifteen (15) major books, including the international bestseller Mind as Healer, Mind as Slayer and Change Your Genes – Change Your Life: Creating Optimal Health with the New Science of Epigenetics.

Today we enjoy the amazing viewpoint that Dr. Pelletier has for humanity. We have control over our destinies individually and collectively. This conversation is the culmination of years of incredible study.

Enjoy,

Dr. M

 

Dr. M’s SPA Newsletter Audiocast Volume 14 Issue 18

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Unraveling the Mysteries of the Amygdala: A review of a section of the book Behave by Robert Sapolsky
In the world of neuroscience, Robert Sapolsky stands as a luminary, a maestro of unraveling the intricate dance of our brain’s circuitry. Among the many deep dives that he delves into, his perspective on the amygdala resonates profoundly for me. The amygdala emerges not as a mere anatomical curiosity as he decides that rather than reducing the amygdala to a simplistic seat of fear and aggression, he highlights its diverse functions, emphasizing its involvement in the vast array of behaviors and experiences. It is a narrative view of the why the brain developed as it did to aid us in the fight against pathogens, predators and stress. Sapolsky’s take on the amygdala is nothing short of revelatory, akin to a seasoned detective peeling away layers of a perplexing case. There are diverse neuronal pathways in this almond-shaped structure nestled deep within our temporal lobes and they have profound purpose. The amygdala emerges not merely as a primal seat of fear and aggression, but as a nuanced orchestrator of our emotional lives. All mammals have emotional responses that are split second to threat, joy and relationship. This is mediated……Plus a section on DNA and memory. Finally, a recipe.
Enjoy,
Dr. M

Dr. M’s SPA Newsletter Audiocast Volume 14 Issue 10

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APOE4 and the history of human disease
Apolipoprotein E, discovered in 1973, is derived from a polymorphic gene called ApoE that encodes for a signaling protein on a class of fatty proteins that primarily carry cholesterol and other molecules around the body. We find ApoE primarily on VLDL, very low-density lipoproteins and HDL, High density lipoproteins. It primarily helps to shuttle cholesterol from the periphery of the body back to the liver. ApoE proteins are also involved in neuronal signaling, neuroinflammation and glucose metabolism making them especially critical for brain activity. This is becoming a critical part of the story for understanding dementia and neurodegeneration. (Williams T. 2020) ApoE is most famous for an isoform, APOE4/4, being highly associated with Alzheimer’s dementia in modernity. Unfortunately, as we do with many things in medicine, we have been focused on this genetic protein variant as a net negative in humans because we look at things as black and white. Either good or bad. A binary choice. Rubish! …..
Enjoy,
Dr. M

Dr. M’s SPA Newsletter Audiocast Volume 14 Issue 7

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This weeks podcast turned out to be so much more than expected when I first heard about Dr. David Clarke. His work transcends much of what I see in clinic and has given a name to the reality of puzzling chronic illness. From the PPDA website: Psychophysiologic disorders (PPD) are stress-related, brain-generated pain or illness. Even people who handle stress well can have PPD. This occurs when the stress is not fully recognized. The resulting symptoms are completely real. That is why the term we use is a blend of Psychology (the processes of the mind) and Physiology (the processes of the body)…..and a discussion on oral allergy syndrome.
Enjoy,
Dr. M

Dr. M’s SPA Newsletter Audiocast Volume 13 Issue 43

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The Power of Suggestion
Can our thoughts affect us at a biological level not just a subjective level?
In a new study published in pre print in BioRxIV entitled: A thalamic circuit represents dose-like responses induced by nicotine-related beliefs in human smokers, we see some new research looking at the power of suggestion well beyond the placebo effect……
Plus a mini literature review as well as a discussion on autism etiology.
Enjoy,
Dr. M

Dr. M’s SPA Newsletter Audiocast Volume 13 Issue 22

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Mental Health and Sleep for teens and college students, Mother’s Day and a poem about mothers.

Here are some highlights: Teenagers are sleep deprived and have been for decades. Nighttime sleep duration has consistently declined over the past few decades. Peak declinations occurred in the late 1990’s and early 2000’s. Girls were less likely than boys to sleep for 7 hours or more per night….
Enjoy,
Dr. M

Dr. M’s Women and Children First Podcast – The Growing Brain and Autism

The Growing Brain and the Upstream Etiologies of Neurodevelopmental disorders – AUTISM
This weeks guest is me! I re-recorded a lecture that I gave in Florida this month at the Annual International Conference for the Institute for Functional Medicine. My goal in this lecture is to look at the upstream reasons that we are seeing more Autism and neurological diversity in children year upon year. It is a wide ranging look at the current state of the science and my thoughts on a unifying theory. As with Dr. Stone’s interview last week with Grow Baby, this is a follow up discussion that is a critical primer for “mother’s to be” regarding disease avoidance measures that can be taken for the best health of the maternal child dyad.
Enjoy,
Dr. M

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