podcast

Dr. M’s Women and Children First Podcast #65 – Mark Houston, M.D. – Cardiovascular Health

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Dr. Mark Houston is a thinker and researcher into the root causes of cardiovascular disease and metabolism. He graduated from Rhodes College in Memphis, Tennessee summa cum laude in Chemistry before graduating with honors from Vanderbilt Medical School. He completed his medical internship and residency at the University of California, San Francisco, then returned to Vanderbilt Medical Center where he was chief resident in medicine and served on the full- time faculty until 2012. He is the current director of the hypertension Institute where he and his team develop novel approaches to hypertension and ASCVD by attending to root biological causes of disease. He also has a Master’s degree in Human Nutrition from the University of Bridgeport, Connecticut, and a Masters of Science degree in Functional and Metabolic Medicine from the University of South Florida in Tampa Florida. He has written hundreds of papers, books and chapters on cardiovascular disease. He is one of the top researchers in the preventative cardiology space and he is here today to share his wisdom.
His book credits:
Handbook of Antihypertensive Therapy
Vascular Biology for the Clinician
What Your Doctor May Not Tell You About Hypertension
Hypertension Handbook for Students and Clinicians
The Hypertension Handbook
What Your Doctor May Not Tell You About Heart Disease.
Please enjoy my conversation with Dr. Mark Houston,
Dr. M
Hypertension Institute

Dr. M’s Women and Children First Podcast #64 – Dan Shapiro, Ph.D. – Provider Burnout

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Dan Shapiro is a man on a mission to help physicians, other providers and the medical healthcare administrators understand the reality of healthcare provider burnout. He is currently the Director of the Chartis Center for Burnout Solutions, where he and his team assist leaders of multi-hospital systems with efforts to reduce burnout and the turnover of high-value physicians, nurses, advanced practice providers, and other staff.

Dan’s education goes back to my alma mater, Vassar College. He graduated with a BA in Psychology before going to the University of Florida for his doctorate in clinical psychology. He completed a post doctoral degree in Medical Crisis Interventions at Harvard University. He held faculty positions at the University of Arizona as well as at Penn State rising to the Chair and Professor of Humanities at Penn State College of Medicine. In 2017, he developed a systematic method for assessing and addressing burnout leading to consulting services focused on multi-hospital systems. In 2023, he left his role as Vice Dean and Chair to pursue the reduction of burnout full time with colleagues at Chartis.

Dan is a frequent contributor to thought leadership in the physician burnout space. In 2003, Random House published his landmark memoir about one physician’s burnout, titled, “Delivering Doctor Amelia,” which was required reading at some colleges and medical schools. He’s written two other books, also for Random House. Dan’s additional writings have appeared or been featured in, among others, the New York Times, Proceedings of the National Academies of Science, the New England Journal of Medicine, JAMA, Academic Medicine, and NPR’s All Things Considered.

As a hobby, he worked for ten years as a weekly consultant to the hit television shows Grey’s Anatomy, Private Practice, How to Get Away with Murder and on-camera for the Discovery, National Geographic, and FYI channels.

Please enjoy my conversation with Dan Shapiro,

Dr. M

Dr. M’s Women and Children First Podcast #63 – David Clarke, M.D. – Pain, Psychology and Trauma

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This weeks guest is Dr. David D. Clarke. Dr. Clarke is President of the Psychophysiologic Disorders Association where he teaches the science of the mind body connection as it relates to GI related diseases that do not fit a traditional diagnostic nor pathological framework. For three plus decades, he conducted detailed interviews with over 7000 people whose symptoms were not explained by diagnostic testing, but were significantly affecting their lives in a negative way. He realized that these individuals often suffered from severe traumas in childhood that built the foundation of current health struggles. We dive into his work and the successes built upon the recognition of, intervention for and resolution related to the issues and physiological manifestations of disease.

Dr. Clarke graduated from Williams College with honors before attending the University of Connecticut School of Medicine where he received his medical degree and the Mosby Award for Clinical Excellence.  He completed internship and residency in Internal Medicine and fellowship in Gastroenterology at Harbor/UCLA Medical Center in Los Angeles. Dr. Clarke has lectured extensively on Psychophysiologic Disorders to specialists and the public across North America and Europe. He has appeared on syndicated broadcasts hosted by Rosie O’Donnell, by Montel Williams and by Michael Roizen(author of You: The Owner’s Manual).

He is the Author of “They Can’t Find Anything Wrong” and co-author of “A Diagnostic Guide for Psychophysiological Disorders” and Psychophysiologic Disorders”.

Please enjoy my conversation with Dr. David Clarke,

Dr. M

Dr. M’s Women and Children First Podcast #62 – Jeff Bland, Ph.D. – The Disease Delusion and Hope for Change

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Podcast #62
Jeff Bland, Ph.D.
This week I have the absolute pleasure to introduce you to Dr. Jeff Bland. He is in a word, incredible.
Dr. Bland is supreme thinker in the field of medicine and biology. He is a teacher, product developer, thought leader, unifier of minds and so much more. He obtained his BS in Biology at the University of California at Irvine and then a PhD from the University of Oregon. Dr. Bland was thinking about medicine from a root cause perspective decades before it became more vogue to believe in Integrative medicine. He is the founder of the Institute for Functional Medicine as well as his new company Big Bold Health, a company on a mission to transform the way people think about one of nature’s greatest innovations — the immune system. With Big Bold Health, he is pushing for the power of cellular immuno-rejuvenation through food to enhance immunity at a human level. The key is the rediscovery of ancient food crops and superfoods that have these properties of health promotion.
We wander the landscape of human health through bramble and brook without a care in the world. It is a most enjoyable conversation to share.
Enjoy,
Dr. M

Dr. M’s Women and Children First Podcast #61 – Bridget Briggs, M.D. – Hope and Epigenetics Part 3

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This is the third story of hope for us as a species. We have a level of control over our outcome that is baked into our DNA.
Bridget R. Briggs, M.D. and I sit down today to discuss the clinical approach to epigenetics in patients especially women. She is a physician who specializes in Women’s Health. Dr. Briggs received her undergraduate degree from the University of California Los Angeles in Psychobiology. She then completed her medical degree from University of California San Diego School of Medicine before completing her residency in family medicine as well as internship in Obstetrics and gynecology. She has been in practice for 25 years in Southern California. She is the owner of two family medicine practices in California where she specializes in functional medicine and womens health. She is a well known speaker and educator on the topics of epigenetics and methylation in humans.
Her story is personal regarding her deep dive into epigenetics and health based on her family’s history and experiences to date. We take a winding road looking at the clinical applications of epigenetic understandings as laid out by the experts and trailblazers of DNA methylation and phenotypic change in animals and humans. We get into some controversial topics including vaccination, preparation for, avoidance of and much more. The conversation is open, honest and thoughtful. We finish with a hard look at the pregnancy state and how to achieve optimal outcomes for our offspring. It is another story of hope for humanity.
Please enjoy my conversation with Dr. Bridget Briggs,
Dr. M

 

Dr. M’s Women and Children First Podcast #60 – Moshe Szyf, Ph.D. – Hope and Epigenetics Part 2

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This week’s guest is Professor Moshe Szyf.
This is the second story of hope for us as a species. We have a level of control over our outcome that is baked into our DNA.
Dr. Moshe Szyf joins the show today to discuss the social programming of the epigenome. Dr. Szyf and his colleague Dr. Meaney proposed over two decades ago the first set of evidence that the “social environment” early in life can alter DNA methylation launching the emerging field of “social epigenetics”. He also has illustrated that DNA methylation is a prime therapeutic target in cancer and other diseases to be explored and potentially manipulated for health.
“Together, they discovered that our genetic code, the actual sequential structure of our DNA, can pretty much shrug off the influence of any external environmental factors, short of massive radiation. However, the expression of individual genes within that sequence can be permanently altered by such seemingly innocuous influences as diet or how others treat us. Once triggered, a group of molecules called a methyl group attaches itself to the control centre of a gene, permanently switching on or off the manufacture of proteins that are essential to the workings of every cell in our body. In most tumours, this DNA methylation pattern has been knocked awry, leading to a gene being completely deactivated or triggered to abnormally high activity.” (McGill Reporter)
Dr. Szyf received his Ph. D from the Hebrew University and did his postdoctoral fellowship in Genetics at Harvard Medical School before he joined the department of Pharmacology and Therapeutics at McGill University in Montreal, Canada. He currently holds the James McGill Professorship in Pharmacology. He is the founding co-director of the Sackler Institute for Epigenetics and Psychobiology at McGill and is a Fellow of the Canadian Institute for Advanced Research Experience-based Brain and Biological Development program. Szyf has been the founder of the first “Pharma” to develop epigenetic pharmacology “Methylgene Inc.” and the first journal in epigenetics “Epigenetics”.
Please enjoy my conversation with Dr. Moshe Szyf,
Enjoy,
Dr. M

Dr. M’s Women and Children First Podcast #59 – Randy Jirtle, Ph. D. – The Imprintome and Hope

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Randy Jirtle, Ph.D.
This week’s guest is Professor Randy Jirtle.
Dr. Randy Jirtle joins the show for the second time today to discuss his new research on the imprintome, the regulatory regions that at the earliest stages of fetal development control our epigentic and thus our genetic outcome. This is the Hope locus.
Time Magazine nominated him for person of the year in 2007 and had this to say about him: “Dr. Jirtle’s pioneering work in epigenetics and genomic imprinting has uncovered a vast territory in which a gene represents less of an inexorable sentence and more of an access point for the environment to modify the genome. His trailblazing discoveries have produced a far more complete and useful understanding of human development and diseases” — Time Magazine. This interview is ground zero for the Women and Children First Podcast as we discuss the underpinnings or mechanisms of disease risk for all humans as it relates to the environmental inputs of our lives that are driving health or disease at both the pregnancy and post natal periods. We look specifically at how maternal nutrition and later chemical exposure directly affected the health of the agouti mouse offspring. This experiment was the first of its kind and paved the way for a complete shift in human disease understanding. For parents, this podcast is really the beginning of everything that I am trying to convey regarding a healthy pregnancy and childhood. Without this interview, the following interviews will be more difficult to understand. The picture becomes very clear once his research is cemented in our minds.
His biography is as follows: Professor of Epigenetics at the Department of Biological Sciences, North Carolina State University, Raleigh, NC, and a Senior Scientist at McArdle Laboratory for Cancer Research at the University of Wisconsin, Madison, WI. He was previously professor of radiation oncology and associate professor of pathology at Duke University, Durham, NC, where he had been a faculty member since 1977. He graduated with a B.S. degree in nuclear engineering in 1970 and a Ph.D. degree in radiation biology in 1976, from the University of Wisconsin-Madison. His awards list is long but the key to Dr. Jirtle is that he is a curious thinker and we are grateful for this.
Please enjoy my conversation with Dr. Randy Jirtle,
Enjoy,
Dr. M

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