Tag Archives: chemicals

Dr. M’s SPA Newsletter Volume 14 Issue 46

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Lymphatics – Refresher

Lymphatics – a plumbing system that follows the circulatory system throughout the body including the brain where it is called the glymphatics. The function of these passively moving tubes is to transport fats around the body, clear cellular debris returning it to the liver and spleen, move fluid in and out of tissue to maintain fluid balance, transport and help immune cells function. By transporting fats , lymph is involved in vitamin movement to tissues and cells for Vitamins A, D, E, K. These are critical functions of metabolism, immunity and detoxification that when disrupted lead to chronic diseases of aging including edema, hypertension, autoimmunity and cardiovascular disease.

“Traditionally considered a passive route for transport of fluid, immune cells, and lipoproteins, lymphatics are now known to be active players in major physiological and pathophysiological processes. Until recently, lymphatic vessel dysfunction was mainly associated with primary and secondary lymphedema. Unexpectedly, however, lymphatic vascular defects have been uncovered in conditions such as obesity, cardiovas- cular disease, inflammation, hypertension, atherosclerosis, Crohn’s disease, glaucoma and various neurological disorders such as Alzheimer’s disease.” (Oliver et. al. 2021)…and a discussion on chemicals in school food.

Enjoy,

Dr. M

Dr. M’s SPA Newsletter Audiocast Volume 14 Issue 31

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Epigenetics and Pregnancy
Epigenetics is the study of environmental signals and their effects on our genes. Our genes are not altered so much as they are read and used differently based on the environmental inputs. Epigenetic effects are critical during the pregnancy period as the environmental signals can alter an offspring’s outcome both in good and bad ways. Making sure that we control for better environmental signal exposure while pregnant can go a long way to protecting our children’s DNA from dysfunction and thus their outcome with health. It is well known that chemicals are generally negative insults to our epigenome while anti-inflammatory whole foods are positive. These epigenetic marks can be conserved over multiple generations making them extraordinarily beneficial or dangerous. Here we will discuss the lifestyle mitigating factors for a positive pregnancy and newborn outcome….plus an ode to Brenda Wassum.
Dr. M

Dr. M’s SPA Newsletter Audiocast Volume 14 Issue 6

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Literature Review
1) Psilocybin is showing further signs of great promise in the fight against depression and PTSD. Psychedelic assisted psychotherapy has gained a foothold in the mainstream of treatment interventions for treatment resistant depression and PTSD. Psilocybin comes from a mushroom that has serotonergic effects on the receptor 5HT2A in the human brain. The results of the studies were net positives in reducing major mood disorder symptoms that are known to be long term in effect. (Haikazian et. al. 2023) I am very excited to see this therapeutic space expand into traumatized teens and other subsets to see outcome benefits. 2) Nanoplastics in the research in the Journal PNAS….. And a section on Antibiotic resistance.
Enjoy,
Dr. M

Dr. M’s SPA Newsletter Audiocast Volume 12 Issue 46

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This week we look at PFAS Chemicals – Otherwise called “Forever Chemicals”

Per- and polyfluoroalkyl substances (PFAS) or forever chemicals are being found all throughout the world as their use has risen over the past 6 plus decades. PFAS are a family of chemicals known as POPS or persistent organic pollutants as they are reported to not break down easily. They have been found in products like Teflon based nonstick cookware, Scotch Guard and Gortex stain-resistant carpeting and clothing, dental floss, commercial firefighting foams and many types of food packaging. Unfortunately, these toxins have been detected in drinking water, house dust and foods/beverages of common consumption…..
We will also discuss children’s strengths and hospitals.
Enjoy,
Dr. M

Dr. M’s Women and Children First Podcast #4 – Ken Cook, the Environmental Working Group and Your Health

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Ken Cook, President and co-founder of the Environmental Working Group, is widely recognized as one of the environmental community’s most prominent and influential critics of industrial agriculture, U.S. food and farm policy and the nation’s broken approach to protecting families and children from toxic substances. Under Cook’s guidance, the organization empowered American families with easy-to-use, data-driven tools to help reduce their exposure to potentially harmful ingredients in foods, drinking water, cosmetics and other household products. These unique digital resources are searched hundreds of millions of times by consumers. 
We discuss the state of the nation with regards to environmental triggers of disease which can cause problems in mothers and children. It is a conversation that every parent needs to hear as it is loaded with news to use for a healthier life.
Please enjoy my conversation with Ken Cook,
Dr. M
Here are two links to the podcast:
Apple Podcasts
Women and Children First
SPA Podcast Page – will be loaded this week

Dr. M’s Women and Children First Podcast #3 – Dr. Randy Jirtle and the Discovery of Maternal Risk

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Dr. Randy Jirtle joins the show today to discuss his groundbreaking research that ushered in the era of epigenetics. Time Magazine nominated him for person of the year in 2007 and had this to say about him: “Dr. Jirtle’s pioneering work in epigenetics and genomic imprinting has uncovered a vast territory in which a gene represents less of an inexorable sentence and more of an access point for the environment to modify the genome. His trailblazing discoveries have produced a far more complete and useful understanding of human development and diseases” — Time Magazine. This interview is ground zero for the Women and Children First Podcast as we discuss the underpinnings or mechanisms of disease risk for all humans as it relates to the environmental inputs of our lives that are driving health or disease at both the pregnancy and post natal periods. We look specifically at how maternal nutrition and later chemical exposure directly affected the health of the agouti mouse offspring. This experiment was the first of its kind and paved the way for a complete shift in human disease understanding. For parents, this podcast is really the beginning of everything that I am trying to convey regarding a healthy pregnancy and childhood. Without this interview, the following interviews will be more difficult to understand. The picture becomes very clear once his research is cemented in our minds.

His biography is as follows: Professor of Epigenetics at the Department of Biological Sciences, North Carolina State University, Raleigh, NC, and a Senior Scientist at McArdle Laboratory for Cancer Research at the University of Wisconsin, Madison, WI. He was previously professor of radiation oncology and associate professor of pathology at Duke University, Durham, NC, where he had been a faculty member since 1977. He graduated with a B.S. degree in nuclear engineering in 1970 and a Ph.D. degree in radiation biology in 1976, from the University of Wisconsin-Madison. His awards list is long but the key to Dr. Jirtle is that he is a curious thinker and we are grateful for this.

Please enjoy my conversation with Dr. Randy Jirtle,

Dr. M