Tag Archives: stress

Dr. M’s SPA Newsletter Audiocast Volume 13 Issue 51

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Literature Review
1) High resting cardiac vagal tone or control, CVC, is associated with more flexible emotional responding to external stressful stimuli. With regard to vagal changes the evidence shows us that stress will decrease CVC . (Balzarotti et. al. 2017)
Being relaxed and not stressed out is always associated with better cellular physiology. CVC is a marker of relaxation and thus emotional control. Whenever you find yourself emotionally dysregulated, there is a good chance that your vagal tone is off. Work to meditate, exercise and relax which will increase CVC and help you cope.
2) Continuing on the same theme….. plus a discussion on maternal neural hormonal rewiring, and a recipe of the week.

Dr. M’s Women and Children First Podcast #60 – Moshe Szyf, Ph.D. – Hope and Epigenetics Part 2

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This week’s guest is Professor Moshe Szyf.
This is the second story of hope for us as a species. We have a level of control over our outcome that is baked into our DNA.
Dr. Moshe Szyf joins the show today to discuss the social programming of the epigenome. Dr. Szyf and his colleague Dr. Meaney proposed over two decades ago the first set of evidence that the “social environment” early in life can alter DNA methylation launching the emerging field of “social epigenetics”. He also has illustrated that DNA methylation is a prime therapeutic target in cancer and other diseases to be explored and potentially manipulated for health.
“Together, they discovered that our genetic code, the actual sequential structure of our DNA, can pretty much shrug off the influence of any external environmental factors, short of massive radiation. However, the expression of individual genes within that sequence can be permanently altered by such seemingly innocuous influences as diet or how others treat us. Once triggered, a group of molecules called a methyl group attaches itself to the control centre of a gene, permanently switching on or off the manufacture of proteins that are essential to the workings of every cell in our body. In most tumours, this DNA methylation pattern has been knocked awry, leading to a gene being completely deactivated or triggered to abnormally high activity.” (McGill Reporter)
Dr. Szyf received his Ph. D from the Hebrew University and did his postdoctoral fellowship in Genetics at Harvard Medical School before he joined the department of Pharmacology and Therapeutics at McGill University in Montreal, Canada. He currently holds the James McGill Professorship in Pharmacology. He is the founding co-director of the Sackler Institute for Epigenetics and Psychobiology at McGill and is a Fellow of the Canadian Institute for Advanced Research Experience-based Brain and Biological Development program. Szyf has been the founder of the first “Pharma” to develop epigenetic pharmacology “Methylgene Inc.” and the first journal in epigenetics “Epigenetics”.
Please enjoy my conversation with Dr. Moshe Szyf,
Enjoy,
Dr. M

Dr. M’s SPA Newsletter Audiocast Volume 13 Issue 46

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Delaying Gratification and Dopamine
When we think of our current societal view on raising children, we have a conundrum. We want our children to experience the world as it is progressing through a technological viewpoint, a growth mentality. What does that mean? . When technology enters the learning process, we progress at log rates. We can process more information and incorporate it into our memory. For a simple example, let’s look back in time. When I was in school, I had to go to the library and search through the library’s archaic dewey decimal system to find a book to reference for information for a project or assignment. Time wasting to say the least compared to the internet age. It took forever to accumulate old data that was in a book. No real time action…Also a mini literature review and a recipe of the week.
Enjoy,
Dr. M

Dr. M’s SPA Newsletter Audiocast Volume 13 Issue 45

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Nature Deprivation Disorder: As we are getting closer to the end of the year and the cold strikes us hard in the face, we have a tendency to hunker down indoors and avoid the outside. Video games and screens are omnipresent in many of our children’s lives. They pervade their thoughts. They significantly limit their self-driven need and desire to explore, imagine and be present with nature, silence and life as it exists around them. Nature and natural actions are some of the best teachers of rational action and normalcy in any ecosystem….Autism etiology and a recipe round out the week.

Enjoy,

Dr. M

Dr. M’s Women and Children First Podcast #58 – Mahmoud Ghannoum, Ph. D. – Microbiomes – Bacterial and Fungal

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This week’s guest is Professor Mahmoud Ghannoum. For over four decades, Dr. Ghannoum has been exploring a critical but neglected inhabitant of the human body, the fungus. Born and raised in Lebanon, Dr Mahmoud Ghannoum is the current Director of the Center for Medical Mycology at Case Western Reserve University. He began his scientific journey at Loughborough University in England where he studied the fungus candida and its health associated diseases. Coupling this work to his curiosity about the whole area of intestinal microorganisms in the human body, he has become one of the leading researchers in the world in this space.
His discoveries include the knowledge that fungal organisms constitute an essential part of the microbiome. In fact, in 2010, Dr Ghannoum was the first scientist to identify over 100 native species of fungi in the oral cavity and that they are mostly friendly to us. Like with bacteria, there are good fungi as well as bad fungi. And just as it was startling to discover that we need positive bacteria in our guts, most people today are shocked to learn that their health depends on flourishing colonies of helpful fungi. Symbiosis in all things seems to be the flavor of the day and history has proven this to be what we should have always assumed.
He is widely published in top journals as well as being the founder and director of Biohm, a company dedicated to microbiome analysis and management from the perspective of fungal and bacterial communities. He is the author of Total Gut Health. This week, Dr. Ghannoum and I look critically at the microbiome of humans from the well trafficked bacterial road to the less travelled fungal road.
Enjoy,
Dr. M

Dr. M’s SPA Newsletter Audiocast Volume 13 Issue 38

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Literature Review

1) “Attention deficit hyperactivity disorder (ADHD) is a common mental behavioral disorder in children. Alterations in gut microbiota composition are associated with neurological disorders….Also discussions on CTE, Covid, Omega 3 Fats, and more…
Part II is about learning how to talk to your children and finally the recipe of the week.
Enjoy,
Dr. M

Dr. M’s SPA Newsletter Audiocast Volume 13 Issue 22

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Mental Health and Sleep for teens and college students, Mother’s Day and a poem about mothers.

Here are some highlights: Teenagers are sleep deprived and have been for decades. Nighttime sleep duration has consistently declined over the past few decades. Peak declinations occurred in the late 1990’s and early 2000’s. Girls were less likely than boys to sleep for 7 hours or more per night….
Enjoy,
Dr. M

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